GLP-1/GIP/Glucagon Receptor Triple Agonist
GLP-3 Research Peptide
GLP-3 is a synthetic peptide classified as a triple receptor agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously. It is supplied as a lyophilized powder for laboratory research applications.
Compound identity
- Name
- GLP-3
- Class
- GLP-1/GIP/Glucagon Receptor Triple Agonist
- CAS number
- 2381404-14-6
- Molecular formula
- C262H398N68O81
- Also known as
- LY3437943, GLP-1/GIP/Glucagon triagonist
Research context
GLP-3 (LY3437943, CAS 2381404-14-6) is a member of an emerging class of incretin-based research compounds. As a triple receptor agonist it is studied in preclinical models for its receptor-binding pharmacology across three metabolic signaling pathways.
The scientific literature on GLP-1/GIP/glucagon multi-agonists examines their receptor specificity and downstream signaling in in-vitro and animal-model systems. Phase-level clinical studies have been reported in peer-reviewed literature; the compound is not approved by the FDA or any regulatory agency for human therapeutic use.
DMV Research supplies GLP-3 with a per-batch third-party Certificate of Analysis confirming identity and purity for research use.
Frequently asked questions
What is GLP-3?+
GLP-3 (LY3437943) is a synthetic peptide studied as a triple agonist at the GLP-1, GIP, and glucagon receptors. CAS 2381404-14-6. It is used as a research reference compound.
How does GLP-3 differ from GLP-1 agonists like semaglutide?+
Single GLP-1 agonists target only the GLP-1 receptor. GLP-3 is a triple agonist that also targets GIP and glucagon receptors, making it a structurally distinct research compound with different receptor pharmacology.
Is GLP-3 approved for human use?+
No. GLP-3 is not approved for human use by any regulatory agency. It is supplied for laboratory and research purposes only.
What purity is the GLP-3 research peptide?+
Each batch is independently tested to 99%+ purity by third-party laboratories, with a Certificate of Analysis available per batch.
Research use only
All products are intended for laboratory and research use only (RUO) and are not for human consumption, ingestion, or any in-vivo use.
The statements on this page have not been evaluated by the FDA. GLP-3 is not intended to diagnose, treat, cure, or prevent any disease. Content is provided for laboratory research reference only.