GH Fragment Peptide
AOD-9604 Research Peptide
As of 2026-08-23, DMV Research documents AOD-9604 (CAS 221231-10-3) across 4 research FAQs on this page, for laboratory research use only.
AOD-9604 is a synthetic peptide fragment corresponding to residues 176-191 of human growth hormone (hGH), modified with an N-terminal tyrosine residue. It is supplied as a lyophilized powder for laboratory research applications.
For laboratory research use only. Not for human or veterinary use. Not for diagnostic or therapeutic use. Not a drug, food, cosmetic, or dietary supplement.
Compound identity
- Name
- AOD-9604
- Class
- GH Fragment Peptide
- CAS number
- 221231-10-3
- Molecular formula
- C78H125N23O23S2
- Also known as
- AOD9604, hGH Fragment 176-191, hGH 177-191 analog
- Sequence
- Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Research context
AOD-9604 (CAS 221231-10-3) is a 16-amino-acid peptide fragment derived from the C-terminal domain of human growth hormone. The compound consists of hGH residues 176-191 with a tyrosine appended at the N-terminus, and contains an internal disulfide bond (Cys-Cys). As a research reagent it is studied for its distinct pharmacological profile relative to full-length hGH in adipocyte cell systems.
The scientific literature on the hGH C-terminal fragment has examined its behavior in in-vitro cell assays and preclinical animal models in the context of adipose tissue biology and lipid metabolism research. AOD-9604 does not contain the N-terminal domain of hGH associated with IGF-1 stimulation, giving it a distinct binding profile that has been characterized in laboratory settings. It is not approved for human therapeutic use by the FDA or any regulatory agency.
Research-grade AOD-9604 is typically supplied with a per-batch third-party Certificate of Analysis confirming identity and purity for research use.
Related research
AOD-9604 is profiled alongside DMV Research's other gh fragment peptide overviews, including MOTS-c, HGH Fragment 176-191, PEG-MGF, hGH C-Terminal Fragments — AOD-9604 & HGH Fragment 176-191 Research Hub, Retatrutide, Semaglutide, and Tirzepatide — each with its own identity data, cited literature, and FAQ. See the AOD-9604 Certificate of Analysis for lab-verified purity data.
Frequently asked questions
What is AOD-9604?+
AOD-9604 is a synthetic peptide fragment consisting of the C-terminal 16 amino acids of human growth hormone (hGH residues 176-191) with an N-terminal tyrosine modification. CAS 221231-10-3. It is used as a research reference compound in adipocyte and metabolic biology research.
How does AOD-9604 relate to human growth hormone?+
AOD-9604 is derived from the C-terminal domain of hGH (positions 176-191 plus a Tyr). It does not include the N-terminal domain responsible for hGH anabolic signaling and IGF-1 release, making it a structurally distinct research compound with a different receptor-binding profile.
Is AOD-9604 approved for human use?+
No. AOD-9604 is not approved for human use by any regulatory agency. As a research compound, it is for laboratory and research purposes only.
What purity is the AOD-9604 research peptide?+
Each batch is independently tested to 99%+ purity by third-party laboratories, with a Certificate of Analysis available per batch.
Research use only
All products are intended for laboratory and research use only (RUO) and are not for human consumption, ingestion, or any in-vivo use.
The statements on this page have not been evaluated by the FDA. For laboratory research use only. Not for human or veterinary use. Not for diagnostic or therapeutic use. Not a drug, food, cosmetic, or dietary supplement.